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Chronic enterocyte infection with coronavirus

Identifieur interne : 001696 ( Main/Exploration ); précédent : 001695; suivant : 001697

Chronic enterocyte infection with coronavirus

Auteurs : S. J. Baker [Inde] ; M. Mathan [Inde] ; V. I. Mathan [Inde] ; S. Jesudoss [Inde] ; S. P. Swaminathan [Inde]

Source :

RBID : ISTEX:A8DDCE818426F5BE839656EA69604675186D4FF3

English descriptors

Abstract

Summary: A man with a gastrojejunostomy and intestinal malabsorption was found to be excreting large numbers of coronavirus-like particles in his stools over a period of at least eight months. Coronavirus-like particles were found in vesicles in degenerating jejunal enterocytes in all of five jejunal biopsies. In a review of electron micrographs, similar structures were found in biopsies from three of 12 patients with classical chronic tropical sprue and in one patient with a sprue-like syndrome associated with agammaglobulinaemia. The hypothesis is advanced that infection with this virus may produce enterocyte damage and may be one cause of the syndrome of tropical sprue.

Url:
DOI: 10.1007/BF01391753


Affiliations:


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Le document en format XML

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<term>Acute gastroenteritis</term>
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<term>Boniface hospital</term>
<term>Canine coronavirus</term>
<term>Coronavirus</term>
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<term>Degenerating</term>
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<term>Experimental enteric infection</term>
<term>Fecal</term>
<term>Fecal extracts</term>
<term>Gastroenteritis</term>
<term>Indian patients</term>
<term>Intestinal</term>
<term>Intestinal infection</term>
<term>Intestinal malabsorption</term>
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<term>Jejunal aspirates</term>
<term>Jejunal biopsies</term>
<term>Jejunal biopsy</term>
<term>Malabsorption</term>
<term>Mathan</term>
<term>Negative staining</term>
<term>Neonatal dogs</term>
<term>Pleomorphic particles</term>
<term>Present case</term>
<term>Present patient</term>
<term>Southern india</term>
<term>Sprue</term>
<term>Stool extracts</term>
<term>Syndrome</term>
<term>Tache avenue</term>
<term>Tissue sections</term>
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<term>Ultramicroscopic changes</term>
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